JHLT: The Podcast

JHLT: The Podcast returns with an episode discussing the paper, "Impact of evolocumab on coronary physiology and microstructure in de-novo heart transplant recipients," from the January issue of JHLT.
Featured on this episode is early career guest host Bin Yang, MD, of Massachusetts General Hospital. Mentored by Digital Media Editor Van-Khue Ton, MD, PhD, Dr. Yang shares hosting duties this episode and brings great questions to the discussion.
Drs. Yang and Ton are joined by the first author, Salma Karim, and senior author, Hans Eiskjaer, both from Aarhus University Hospital in Denmark.
The discussion explores:
What imaging and physical markers the researchers used to determine if evolocumab was influencing the development of cardiac allograft vasculopathy (CAV)
The potential role of lipid-lowering therapies or statins in treating CAV
The relationship between CAV and microvascular resistance (IMR)
For the latest studies from JHLT, visit www.jhltonline.org/current, or, if you're an ISHLT member, access your Journal membership at www.ishlt.org/jhlt.
In case you missed it, earlier this month the JHLT Digital Media Editors recapped their favorite papers from 2025. Take a listen!
Don't already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.

Happy new year and welcome to a new season of JHLT: The Podcast! In this year-end recap, the Digital Media Editors will each share one of their favorite studies from The Journal of Heart and Lung Transplantation in 2025. You'll get a look at some of the best science in advanced heart and lung failure from the past year.
 
Studies featured:
Efficacy and safety of sotatercept across ranges of cardiac index in patients with pulmonary arterial hypertension: A pooled analysis of PULSAR and STELLAR
Gomberg-Maitland M, et al. JHLT Apr 2025 44(4):609 – 624.
A consensus-based framework for the psychosocial evaluation of pediatric candidates for cardiothoracic transplant and ventricular assist devices
Lefkowitz DS, et al. JHLT Apr 2025 44(4):487-502.
ABO-incompatible heart transplants in children aged 2-9 years: A new paradigm in transplant?
Hollis P, et al. JHLT Dec 2025 44(12):1910-1917.
Heart transplantation in Ukraine during wartime: A retrospective cohort study of standard vs marginal donor heart transplantation outcomes
Todurov B, et al. JHLT Nov 2025 44(11):1728-1734.
 
For the latest studies from JHLT, visit www.jhltonline.org/current, or, if you're an ISHLT member, access your Journal membership at www.ishlt.org/jhlt.
 
Don't already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.

JHLT: The Podcast returns with an episode discussing the paper, "High Antiphospholipid Antibody Titers and Outcomes of Pulmonary Endarterectomy: A Single-Center Retrospective Observational Cohort Study," from the December issue of JHLT.
 
They are joined by the first author, Camille Miard, MD, and senior author, François Stéphan, MD, PhD, both from the cardiothoracic intensive care unit at Hôpital Marie Lannelongue in Paris.
 
The discussion explores:
Whether antiphospholipid antibody titers could predict postoperative outcomes for CTEPH patients undergoing pulmonary endarterectomy (PEA)
How APS patients differed from non-APS patients in the PEA cohort
The changes in clinical practice at Marie Lannelongue after the study's findings
 
For the latest studies from JHLT, visit www.jhltonline.org/current, or, if you're an ISHLT member, access your Journal membership at www.ishlt.org/jhlt.
 
Don't already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.

On this episode of JHLT: The Podcast, the Digital Media Editors host a discussion on the paper, "Lung transplant in patients with suspicious lung lesions: A single-center retrospective data analysis," which appears in the December issue of JHLT.
They are joined by the senior author, Stefan Schwarz, MD, PhD, of the Department of Thoracic Surgery at the Medical University of Vienna.
The discussion explores:
Methods used to assess the probability of malignancy in the patient cohort
The limitations of common scanning methods in assessing this type of transplant patient
What the study confirms or changes about standards in clinical practice
For the latest studies from JHLT, visit www.jhltonline.org/current, or, if you're an ISHLT member, access your Journal membership at www.ishlt.org/jhlt.
Don't already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.

On this episode of JHLT: The Podcast, the Digital Media Editors host a discussion on the paper, "Impact of donor specific antibodies on longitudinal lung function and baseline lung allograft dysfunction."
 
They are joined by the first author, Muhtadi Alnababteh, MD, Assistant Professor at the University of Maryland and Staff Clinician at the National Institutes of Health, and senior author Michael Keller, MD, of the Pulmonary and Critical Care division at the University of Maryland.
 
The discussion explores:
Common characteristics of patients who developed donor-specific antibodies (DSA)
Differences in outcomes depending on when DSA developed
Associations between the development of DSA and antibody-mediated rejection, and related time frames
For the latest studies from JHLT, visit www.jhltonline.org/current, or, if you're an ISHLT member, access your Journal membership at www.ishlt.org/jhlt.
 
Don't already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.