Ep. 306: “Vertebrate Development” Featuring Dr. Carole LaBonne
Dr. Carole LaBonne is the Erastus Otis Haven Professor of Molecular Biosciences at Northwestern University. Her lab studies the genesis of neural crest stem cells at the level of the signaling pathways and transcription factors that comprise the neural crest gene regulatory network. They also study how these mechanisms contribute to exit from pluripotency and the subsequent lineage restriction of neural crest cells to their derivative cell types that collectively define vertebrates.
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1:11:46
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1:11:46
Ep. 305: “Glial Cell Fate” Featuring Dr. Paul Tesar
Dr. Paul Tesar is the Director of the Institute for Glial Sciences and the Dr. Donald and Ruth Weber Goodman Professor of Innovative Therapeutics at Case Western Reserve University. His lab uses PSCs to model neurological development and disease with a specific focus on oligodendrocytes and astrocytes. He talks about his work on oligodendrocyte maturation, advancing research into the commercial and clinical sectors, and mentoring the next generation of scientists.
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1:24:25
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1:24:25
Ep. 304: “Gene Regulation” Featuring Dr. Lars Velten
Dr. Lars Velten is a Group Leader at the Centre for Genomic Regulation in Barcelona. He talks about his research on cell-state-specific enhancers in hematopoiesis and lineage tracing techniques to study blood aging. He also discusses combining generative AI with wet lab techniques and the advantages of risk-taking in basic research.
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1:15:19
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1:15:19
Ep. 303: “Organoid Models of Cancer” Featuring Dr. Alice Soragni
Dr. Alice Soragni is an Associate Professor at the University of California, Los Angeles. She talks about her work on patient-derived organoids and how they can be adapted for drug screening. She also discusses how she transitioned from structural biology to research on protein aggregation and rare diseases, and the current social media landscape for scientists.
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1:35:25
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1:35:25
Ep. 302: “Kidney Organoids” Featuring Dr. Zhongwei Li
Dr. Zhongwei Li is an Associate Professor at the University of Southern California. His lab focuses on kidney organogenesis with translational applications of kidney regeneration and disease modeling. He talks about his work on PSC-derived nephron progenitors and drug discovery applications for polycystic kidney disease.
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