For Valentina, it was meant to be a new beginning: changing homes and continents, moving to a place where she had felt at home since her very first visit. The diagnosis came just as everything seemed ready—lymphoma. Within a matter of hours, Valentina’s life was turned upside down, and that “new beginning” became a journey into illness, culminating in a personalized treatment that was experimental at the time: CAR T-cell therapy.
Ep.4 - Un nuovo inizio [ITA]
24/04/2026 | 23 min
Per Valentina doveva essere un nuovo inizio, cambiare casa e continente, trasferirsi in un posto nuovo in cui si era sentita a casa fin dalla prima visita. La diagnosi è arrivata quando tutto sembrava pronto: linfoma. Nel giro di poche ore la vita di Valentina è stata stravolta e quel nuovo si è trasformato in un viaggio dentro la malattia, culminato con un trattamento personalizzato, sperimentale per i tempi: la terapia con cellule Car-T.
Ep.3 - The story of Olivia and Dianne, whose hearts have been protected since childhood [ENG]
12/03/2026 | 28 min
Olivia and Dianne are two Dutch teenagers who have lived with a rare disease since birth that causes excessive accumulation of cholesterol in the blood. It is called homozygous familial hypercholesterolemia, affecting less than one child in every 300,000 individuals, and can cause heart attacks from an early age. The standard treatment for this condition is very stressful and invasive, but thanks to advances in personalized medicine, Olivia, Dianne, and others living with this condition can now live peaceful lives like everyone else.
Ep.3 - La storia di Olivie e Dianne, il cuore protetto fin dall’infanzia [ITA]
12/03/2026 | 26 min
Olivia e Dianne sono due adolescenti olandesi che convivono dalla nascita con una rara malattia che causa accumulo eccessivo di colesterolo nel sangue, si chiama ipercolesterolemia familiare omozigote, colpisce meno di un bambino ogni trecentomila individui e può provocare incidenti cardiaci fin dai primi anni di vita. Il trattamento standard di questa condizione è molto stressante invasivo, ma grazie ai progressi nel campo della medicina personalizzata Olivia, Dianne e le altre persone che vivono la loro condizione, possono oggi vivere una vita serena al pari di tutti gli altri.
Ep.2 - Malattie genetiche rare: la storia di Joe, Connie e della loro famiglia [ITA]
21/11/2025 | 24 min
Joe è un adolescente pieno di vita che arriva dal nord dell’Inghilterra. Ama l’Italia perché è qui che è stato curato da una malattia genetica rara, la stessa che ha tolto la vita alla sua sorellina Connie. In questa puntata raccontiamo la sua storia e quella della sua famiglia, per scoprire quali sono le frontiere della medicina personalizzata per le terapie geniche.
SECOND SEASON
Four episodes. Four powerful stories of patients and former patients who benefited from personalised medicine. From oncology to rare genetic disorders, from preventive surgery to cardiovascular diseases, this podcast brings real human experiences to life, showing how tailor-made therapies are reshaping treatment into a more effective and informed journey.
The second season of the Science of You is a Chora Media podcast, supported by the European Partnership for Personalised Medicine, coordinated by Fondazione Toscana Life Sciences. The Science of You is co-funded by the European Union’s Horizon Europe research and innovation programme.
The podcast is hosted by Giulia Bassetto and written by Simone Clemente.
The editorial curation is by Graziano Nani.
Post-production is done by Matteo Zullo.
The project manager is Anna Maria Renda.
The producer is Martina Conte.
Post-production coordination is by Matteo Scelsa.
The graphic project is by Rebecca Grassi.
Sound design is by Luca Possi.
FIRST SEASON
On the surface, we’re all quite similar. But zoom in and our unique biologies and environments reveal differences that shape how we react to certain foods, process medicines, and are susceptible to specific diseases. For a long time, medicine took a one-size-fits-all approach—and sometimes it didn’t fit at all. Now we’re on the cusp of a major shift: a new era where treatments could be tailored to each person’s unique biology. Join Silvia Lazzaris as she speaks with researchers and clinicians at the forefront of this transformation, exploring the discoveries that challenged our understanding of the human body and the innovations set to redefine healthcare. We’ll tackle big questions: Where are we now? What could healthcare look like in the future? And crucially, who will have access to it?
The Science of You is a Chora Media podcast, supported by the European Partnership for Personalised Medicine, coordinated by Fondazione Toscana Life Sciences, and co-funded by the European Union's Horizon Europe research and innovation programme.
The podcast is written and hosted by me, Silvia Lazzaris, with editorial curation by Simone Clemente.
Sound and music supervision is by Luca Micheli.
Post-production and editing are done by Andrea Girelli.
Sound design is by Luca Possi.
The project manager is Silvia Arcidiacono Mutti.
The producer is Martina Conte, with post-production coordination by Matteo Scelsa.
Thanks to Francesco Zaffarano for lending his voice for the voice-over.
Musiche su licenza di Universal Music Publishing Ricordi srl e di Machiavelli Music
Italia