PsychRounds: The Psychiatry Podcast

We resume our landmark studies series looking at the pivotal study in Major Depressive Disorder (MDD), The STAR*D (Sequenced Treatment Alternatives to Relieve Depression) trial.

References:
https://pubmed.ncbi.nlm.nih.gov/12778843/
https://pubmed.ncbi.nlm.nih.gov/19880458/
https://jamanetwork.com/journals/jamapsychiatry/fullarticle/482026
https://pubmed.ncbi.nlm.nih.gov/15061154/
https://pubmed.ncbi.nlm.nih.gov/20370962/
https://pubmed.ncbi.nlm.nih.gov/37491091/

We have a special guest today to talk about one of our favorite topics... dogs! Most people might intuitively say that they feel like their dogs improve their mental health, but today, we look at the science with the leading expert on the subject.

Dr. Nancy Gee Profile: https://medschool.vcu.edu/about/portfolio/details/geen2/

References:
Dogs Supporting Human Health and Well-Being: A Biopsychosocial Approach: 
https://pubmed.ncbi.nlm.nih.gov/33860004/
Randomized Controlled Trials: https://pmc.ncbi.nlm.nih.gov/articles/PMC12728353/, https://pmc.ncbi.nlm.nih.gov/articles/PMC11714157/

Welcome back! Today, we are talking about Simtriyo, which has generated a lot of media attention recently given a newly minted FDA approval for ADHD.

References 
https://pmc.ncbi.nlm.nih.gov/articles/PMC12314114/
https://pmc.ncbi.nlm.nih.gov/articles/PMC12379780/
https://pubmed.ncbi.nlm.nih.gov/31776871/
https://pubmed.ncbi.nlm.nih.gov/40619095/
https://pubmed.ncbi.nlm.nih.gov/28731336/
https://pmc.ncbi.nlm.nih.gov/articles/PMC9426730/

Today we're starting a new type of series - looking at some of the most seminal studies in psychiatry. We're going to start with the CATIE Trial, which was published in 2005.

References:
https://www.nejm.org/doi/full/10.1056/NEJMoa051688
https://pubmed.ncbi.nlm.nih.gov/19594194/
https://pubmed.ncbi.nlm.nih.gov/17924259/
https://pubmed.ncbi.nlm.nih.gov/17286522/
https://www.nejm.org/doi/full/10.1056/NEJMoa061240
https://jamanetwork.com/journals/jamapsychiatry/fullarticle/209844

Apologies for our little hiatus - a couple of us had cross-country moves in June. But we're back! Today we have an episode on the rising use of recreational Kratom and pertinent tidbits to know from a psychiatry standpoint.

References:

https://pmc.ncbi.nlm.nih.gov/articles/PMC8924421/

https://www.ncbi.nlm.nih.gov/books/NBK585120/

https://pmc.ncbi.nlm.nih.gov/articles/PMC10846393/

https://pmc.ncbi.nlm.nih.gov/articles/PMC10177737/