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The General Podcast

The General Partnership
The General Podcast
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  • Inside the COO Role: Claire Hughes Johnson x Gretchen Howard
    Claire Hughes Johnson (former COO at Stripe) and Gretchen Howard (former COO at Robinhood) join The General Podcast for a rare, candid conversation about what it really means to operate at the highest levels inside two of the most ambitious fintech companies of the past decade. Both left safe jobs to take bets that looked “crazy” from the outside. Both joined hyper-growth startups without the COO title, built trust with founders in real time, and ended up shaping the companies from the inside out. In this episode, they dig into what the COO role actually is, how to avoid “organ rejection” when you’re the outsider, and why the people function is the most underrated lever for scaling. You’ll hear Claire and Gretchen swap notes on why the hardest problems are often unglamorous—compliance, self-clearing, comp plans—and why the real work is about earning trust, building velocity, and protecting the integrity of the company as it grows. In this conversation, you’ll learn: Why Claire and Gretchen said yes to Stripe and Robinhood when everyone around them said noTheir takes on founder chemistry and how to know if you can actually work with someoneHow to walk into a COO role without blowing up the cultureWhat founders get wrong when hiring their first COOHow Stripe and Robinhood scaled the ‘unsexy’ parts of businessHow to build systems without adding bureaucracyHow to use the people function as a strategic weaponBeing okay with not being liked as your leadership evolves Claire’s “full stack leader” frameworkWhat great operators actually obsess overWhere to find Gretchen: LinkedIn: https://www.linkedin.com/in/gretchenehowardWhere to find Claire: X: https://x.com/chughesjohnsonLinkedIn: https://www.linkedin.com/in/claire-hughes-johnson-7058Book: Scaling PeopleWhere to find TheGP: X: @thegpNewsletter: https://thegeneralpartnership.substack.com/
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  • Dan Shipper x Alex Konrad
    Dan Shipper is the co-founder and CEO of Every, a media company built around writing, software, and AI. With a tiny team, they put out a daily newsletter, build products, and run a consulting arm, all while staying weird and experimental. Dan’s one of the most thoughtful writers on how AI is reshaping creativity, business, and what it means to build.Alex Konrad is the founder of Upstarts, a newsletter about the next breakout companies before they break out. He spent over a decade at Forbes, where he wrote 15+ cover stories, co-created the Cloud 100 list, and led Midas List coverage of the top VCs in the world. Together, they discuss and debate building sustainable media businesses today, using AI to amplify creativity, and why legacy playbooks no longer apply.In this conversation, you’ll learn:1. Why being weird is often a competitive advantage2. How thinking like a product person (and not just a writer) shapes everything they publish3. The surprisingly tactical ways they protect time for original thinking4. Why Upstarts and Every both resisted the pressure to “build the platform” too soon5. How Every runs multiple AI products and a daily newsletter with only 15 people6. Why they both believe your business model is a creative decision7. Their thinking around independent journalism as a “tech-enabled service,” not content8. How AI tools like Claude, Cora, and ChatGPT actually fit into their creative process9. How to avoid burnout when your business is also your identity10. How to stay joyful and experimental when everyone else is optimizingWhere to find Dan:Newsletter: every.toX: @danshipperWhere to find Alex:Newsletter: https://www.upstartsmedia.comX: @alexrkonradWhere to find TheGP:Newsletter:  https://thegeneralpartnership.substack.com/X: @thegpReferenced in this episode:MrBeast: https://www.youtube.com/@MrBeastThe Pragmatic Engineer: https://www.pragmaticengineer.comStratechery by Ben Thompson: https://stratechery.com/Lenny’s Newsletter: https://www.lennysnewsletter.com/Tom Brady quote: “Winners focus on winning. Losers focus on winners.”Acquired Podcast: https://www.acquired.fm/Claude: https://claude.aiChatGPT: https://chatgpt.com War and Peace by Leo TolstoyThe writer Maggie NelsonSpiral by Every: https://spiral.computerCora by Every: https://cora.computerThink Week (Bill Gates’s famous retreat)Documentary: WeWork: Or the Making and Breaking of a $47 Billion Unicorn 
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  • Christina Farr x Siddhartha Mukherjee
    Christina Farr, longtime healthtech journalist and now advisor, investor, and editor-in-chief of Second Opinion Media, sits down with Siddhartha Mukherjee, Pulitzer Prize–winning author of "The Emperor of All Maladies," oncologist, and founder of Manas AI.In this expansive conversation, they explore the current and future role of AI in medicine. Sid offers a typology for how LLMs are showing up in clinical practice and scientific discovery, while Chrissy pushes on what AI can’t yet replicate: intuition, empathy and institutional memory. They discuss whether AI will replace the “intelligentsia,” what it gets right and wrong about diagnostics and drug discovery, and how clinicians can stay relevant by staying creative. This is a thoughtful, urgent discussion between two people who are both deeply familiar with the systems of medicine. In this conversation, you’ll learn:1. A six-part framework for how AI is transforming healthcare and science2. How ambient scribes, LLMs, and generative chemistry are reshaping workflows3. The difference between simulated empathy and real human care4. What LLMs still miss: texture, taste, and tacit knowledge5. How AI might (or might not) generate revolutionary scientific insights6. Why the future belongs to clinicians who generate new knowledge, not just apply itWhere to find Chrissy:LinkedIn: https://www.linkedin.com/in/christinafarr/X: https://x.com/chrissyfarSubstack: https://secondopinion.media/Where to find Sid:LinkedIn: https://www.linkedin.com/in/siddhartha-mukherjee-19b6b8126/The New Yorker: https://www.newyorker.com/contributors/siddhartha-mukherjeeBooks: The Emperor of All Maladies, The Gene, The Song of the CellWhere to find TheGP: LinkedIn: https://www.linkedin.com/company/the-general-partnershipX: https://x.com/thegpSubstack: https://thegeneralpartnership.substack.com/Referenced in this episode: • Manas AI: https://www.manasai.co• Richard Feynman’s “Cargo Cult Science” lecture: https://calteches.library.caltech.edu/51/2/CargoCult.htm• Thomas Kuhn’s The Structure of Scientific Revolutions: https://www.amazon.com/Structure-Scientific-Revolutions-50th-Anniversary-ebook/dp/B007USH7J2/• Karl Popper’s theory of falsifiability: https://www.simplypsychology.org/karl-popper.html• Stephen Jay Gould’s “The Median Isn’t the Message”: https://journalofethics.ama-assn.org/article/median-isnt-message/2013-01• David Fajgenbaum’s Chasing My Cure: https://chasingmycure.com/
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  • Katie Dill x Randy Hunt
    Katie Dill, Head of Design at Stripe, and Randy Hunt, Head of Design at Notion, sit down to swap stories in the first episode of The General Podcast. This is a conversation between two of the most thoughtful design leaders in tech, covering everything from building taste into products to maintaining creative conviction inside fast-scaling orgs. They discuss how to protect what makes design great, what designers uniquely bring to the table in the age of AI, and why sometimes you just have to pick mint chip and go.In this conversation, you’ll learn:Why beautiful, well-crafted products matter - especially in the age of AIThe case for “fewer memos, more demos” and how Stripe operationalizes qualityHow Notion fosters taste through founder collaboration and radical transparencyA dead-simple metaphor for decision-making: picking one flavor of ice creamThe enduring value of the auteur in design and how to scale convictionWhy prototyping trumps PowerPointsHow both teams use design rituals to stay connectedWhere to find Katie: LinkedIn: https://www.linkedin.com/in/katie-dill-79168b3X: https://x.com/lil_dillWhere to find Randy: LinkedIn: https://www.linkedin.com/in/randyjhunt/X: https://x.com/randyjhuntWhere to find TheGP: LinkedIn: https://www.linkedin.com/company/the-general-partnershipX: https://x.com/thegpSubstack: https://thegeneralpartnership.substack.com/
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  • Introducing The General Podcast
    What is The General Podcast? 
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Su The General Podcast

The General Podcast pairs founders, operators, executives, and creative minds for behind-the-scenes talk about building. No host and no script. Just craft, conviction, and real conversation between peers. Produced by The General Partnership. thegp.com
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