2 mishanyot! 1 - How combinations can make items pigul or not. With the cases of the thanksgiving offering (animal offering plus loaves) and also the "Shtei HaLehem" - lambs and 2 loaves of Shavuot. Also, a long discussion about what question Rabbi Elazar asked of Rav (to determine the question itself), in terms of pigul with varied factors -- the order of events, with regard to offerings, intent, minimal measure, and so on. Plus, a mention of "cannabis" (hemp) in the context of mixtures. 2 - Pigul intent renders the libations pigul once they've been sanctified, but the libations, if brought with pigul intent, would not make the offerings themselves pigul.